Last edited by Micage
Sunday, August 9, 2020 | History

1 edition of Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine found in the catalog.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

by Johnny Huard

  • 68 Want to read
  • 27 Currently reading

Published by Birkhäuser Boston in Boston, MA .
Written in English

    Subjects:
  • Medicine,
  • Sports medicine,
  • Life sciences,
  • Orthopedics,
  • Biomedical engineering

  • About the Edition

    With the development of improved methods of transferring genes into cells, new treatment options are becoming available in orthopaedics and sports medicine to aid in the healing capacity of musculoskeletal tissues. In this book, current techniques in gene therapy and tissue engineering are described in addition to their potential applications in the management of orthopaedic trauma and sports-related injuries such as muscle injury and ligament, meniscus, or cartilage damage. The book bridges the gap between the clinicians aiming to improve recovery following such injuries, and researchers interested in tissue engineering and gene therapy. This book will be read by physicians and researchers in orthopaedic surgery, sports medicine, and cell and molecular biology.

    Edition Notes

    Statementedited by Johnny Huard, Freddie H. Fu
    SeriesMethods in Bioengineering, Methods in bioengineering
    ContributionsFu, Freddie H.
    Classifications
    LC ClassificationsRD701-811
    The Physical Object
    Format[electronic resource] /
    Pagination1 online resource (xvi, 286p. 51 illus.)
    Number of Pages286
    ID Numbers
    Open LibraryOL27040858M
    ISBN 101461274249, 1461221269
    ISBN 109781461274247, 9781461221265
    OCLC/WorldCa853266552

    Gene therapy involves the introduction of foreign genetic material into cells in order exert a therapeutic effect. The application of gene therapy to the field of orthopaedic tissue engineering is extremely promising as the controlled release of therapeutic proteins such as bone morphogenetic proteins have been shown to stimulate bone repair. However, there are a number of drawbacks associated Cited by: T1 - Gene therapy in orthopaedics. AU - Evans, C. H. AU - Robbins, P. D. PY - /1/1. Y1 - /1/1. N2 - Genes are composed of deoxyribonucleic acid (DNA), the hereditary material of all nucleated cells. One way in which genes function is to direct the synthesis of specific by:

    Chapter 28 Gene Therapy and Tissue Engineering Laurie R. Goodrich, DVM, PhD, Diplomate ACVS Chapter 29 Ethics of Articular Cartilage Surgery: Stem Cells, Ex Vivo Manipulation, and Juvenile Sources.   Finally, the possible application of gene therapy in athletes, gene doping and genetic testing of athletes are discussed. The book is highly recommended to exercise scientists, sports clinicians, human geneticists, athletes, coaches and to all those interested in the relatively new area of genetic research within the fields of exercise science.

      To define the early biological effect of in vivo introduction of the PDGF-B gene on the healing of ligaments, a HVJ-liposome suspension containing platelet-derived growth factor (PDGF)-B Cited by:   Next generation tissue engineering of orthopedic soft tissue-to-bone interfaces - Volume 7 Issue 3 - Alexander J. Boys, Mary Clare McCorry, Scott Rodeo, Lawrence J. Cited by: 7.


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Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by Johnny Huard Download PDF EPUB FB2

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine (Methods in Bioengineering) th Edition by Johnny Huard (Editor), Freddie H. Fu (Editor) ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book.

Format: Hardcover. Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine Editors: Huard, Johnny, Fu, Freddie H.

(Eds.) Free Preview. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine. Find all books from Huard J. At you can find used, antique and new books, compare results and immediately purchase your selection at the best price.

[EAN: ], [PU: Birkhauser Verlag AG]. The Paperback of the Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by Johnny Huard at Barnes & Noble. FREE Shipping on $35 or. Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by Johnny Huard,available at Book Depository with free delivery worldwide.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine: Johnny Huard:   Tissue engineering, which may eventually be combined with gene therapy, may potentially result in the creation of tissues or scaffolds for regeneration of tissue defects following trauma.

In this article we will discuss why gene therapy and tissue engineering are becoming increasingly important in modern orthopaedic sports medicine by:   (). Gene Therapy and Tissue Engineering in Sports Medicine.

The Physician and Sportsmedicine: Vol. 28, No. 2, pp. Cited by: from book Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine (pp) Gene Therapy in Orthopaedics Chapter January with 2 Reads.

Introduction. Tissue engineering (TE) approaches are converging with medical sciences and revolutionising the paradigm of sports medicine. TE relies on three essential features: scaffolds, cells and biological factors (eg, growth factors and physical stimuli).1 Combining these three features, TE has shown very promising results.

This novel approach in orthopaedic sports medicine aims to Cited by: 1. Book Condition: Ships same or next working day from UK. Delivered in days (or select two-day/expedited shipping). Your purchase helps support the African Children's Educational Trust (A-CET).

Ex-library, so some stamps and wear, but in good overall condition. % money back : Hardcover. The following chapters in this book aim to provide a profound insight into gene therapy, one of the newest and most exciting aspects of applied biological principles in orthopaedics. Keywords Anterior Cruciate Ligament Gene Therapy Bone Tunnel Healing Response Duchenne Muscular DystrophyAuthor: Christian Lattermann, Freddie H.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine. [Johnny Huard; Freddie H Fu] -- With the development of improved methods of transferring genes into cells, new treatment options are becoming available in orthopaedics and sports medicine to aid in.

The Potential of Gene Therapy for Osteogenesis Imperfecta / Christopher Niyibizi, Patrick N. Smith and Joel Greenberger. The Role of Nitric Oxide as a Candidate Molecule for Gene Therapy in Sports Injuries / Scott A. Rodeo and Kazutaka Izawa --Pt. III. Tissue Engineering in.

Besides the treatment of genetic diseases, gene therapy has been developed and clinically tested in several other areas, such as cancer, cardiovascular disease and orthopaedics.4, 77, 90 A study in rheumatoid arthritis was the first to use gene therapy for a nonlethal disease, 31Cited by: Orthopaedic applications of gene therapy.

It is possible to define four areas of orthopaedics where gene therapy might be clinically useful [Evans et al., a]: Mendelian disorders; tumors; arthritis and other joint diseases; tissue repair and regenerative medicine (TERM).Although there has been some pre-clinical progress in addressing genetic diseases such as osteogenesis imperfecta and the Cited by: Gene therapy has the potential to revolutionize the treatment of a variety of musculoskeletal disorders.

In the past decade, more than 4, patients have been enrolled in clinical trials. Tissue engineering, the science of generating living tissues, holds promise for treating human disease. Specific to the field of orthopaedics, tissue engineering strategies are being investigated for a number of challenging musculoskeletal pathologies, including fracture nonunion, osteonecrosis, and osteochondral by: Stem Cell and Gene-Based Therapy: Frontiers in Regenerative Medicine is written by the leading figures in the field of stem cells, gene therapy and tissue engineering and covers the major approaches to regenerative medicine, ensuring that techniques learnt in one discipline are disseminated across other areas of medicine.

This allows. presented. Using this method, genes have been delivered successfully into tissues of orthopaedic importance with high-efficiency by nonviral means. Transforming growth factor-beta 1, parathyroid hormone related protein, and a marker gene were transfected into primary perichondrium and cartilage cells with efficiencies in excess of 70%.

They overexpressed their cognate gene products showing. Part two focuses on the different applications of bioactive materials in medicine, with chapters discussing applications in orthopaedics, in the circulatory system,and as antibacterials.

The final chapters focus on the uses of these materials in gene therapy, plastic surgery and body reconstruction, and in .Gene Therapy, Tissue Engineering for Sports Injuries Mar AM EST, by American Academy of Orthopaedic Surgeons (AAOS) For A.M.

Release Fri., Ma   This book explores the basic science and clinical concepts impacting bone tissue engineering; considers advances in gene therapy for enhancement of bone and cartilage repair; and presents the biomechanical factors affecting articular cartilage by: